After having owned both, hands down, stock to stock, as delivered, the Non-Intercooled trucks will run circles around the intercooled ones.
The non-intercooled engines have less "emissions" related crap and they definitely are the better stock performer.
I've honestly never had much faith in the stock intercooler.
It's best replaced with a Power Stroke, or 2nd gen unit, to get rid of that restriction up front.
While the non-intercooled piston is the wider 155* bowl, the injector is also the same 155*, so there really is no potential gain from a timing bump, you STILL can run the spray out of the bowl.
Now, run a 145* injector into a 155* bowl and you have something you can put more advance into.
But wait... Why advance the crap out of timing on a VE, when it's technically a low rpm pump?

Mark.